Improving Gut Permeability

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About Course

The intestinal wall serves as an essential barrier and front with respect to the human immune system. Numerous foods and nutrients have clinically demonstrated an ability to alter the size of the tight junctions that lie between the epithelial cells which comprise the brush border. The size of these gap junctions ultimately determines the level of permeability allowed by the gut wall.

Both dietary ingredients and microbial populations play pivotal roles in the maintenance of brush border mucosal integrity and tight junction configurations. Discover how the intestinal environment and dietary patterns influence the challenges presented to the immune system and the level to which specific proteins enter circulation.

Key words: zonulin, occluding, tight junction, gap junction, mucosal, commensal, SCFAs

References: Improving Gut Permeability References

APPROVED FOR 1 CPE CREDIT BY THE CDR OF THE ACADEMY OF NUTRITION AND DIETETICS
RDs may claim CE credit for this webinar until 5/27/2024.

Make sure to check to out the Continuing Education Guide for instructions on how to complete and earn your credit for this course!

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What Will You Learn?

  • 1. Identify the role of tight junctions in maintaining normal absorption and immune system function.
  • 2. List those foods and/or nutrients that have been clinically proven to alter the width of tight junctions.
  • 3. Describe at least 3 dietary patterns that compromise gut wall integrity
  • 4. Explain how clinicians can address excessive intestinal permeability through both dietary and microbial interventions.