Mitochondrial disease

A recent Dutch study last month, published in the Journal of Parenteral and Enteral Nutrition, revealed that those populations with neurodegenerative diseases caused by mitochondrial dysfunction are most often malnourished in at least a few to multiple macro and micronutrients. Mitochondrial pathology is at the core of many diseases, most of which are on significant rise globally.  Mitochondria require quite possibly the greatest nutritional support of any organelle within our cellular physiology.  When nutrients are missing from an individual's diet and mitochondria are unsupported, they start to burn out. Eventually, after there is sufficient damage, entire neurons start to collapse metabolically. It is this collapse that generates symptoms and ultimately the disease state.

While we recognize several micronutrients that are most often missing in diets and that can leave mitochondria vulnerable, there are also several ingredients in most population diets that equally undermine mitochondrial health: the polyunsaturated fats in seed oils (canola, soybean, sunflower, safflower, corn) and fructose (fruit juice concentrates, agave, corn syrup, cane sugar, sugar in most cases).

Functional Formularies is proud to offer not only enteral formulas that are nutritionally complete and which are also free of those damaging ingredients.  Additionally, Liquid Hope and Nourish contain an array of beneficial plant-based molecules from many of our organic, whole food, plant ingredients.  Whether an individual is trying to avoid a mitochondrial issue or a patient with a mitochondrial disorder/neurodegenerative disease is trying to mitigate its effects, whole foods and nutrient-dense are essential.

 ~ John Bagnulo MPH, PhD.

 

Reference:
Zweers H et al. Patients With Mitochondrial Disease Have an Inadequate Nutritional Intake. 2017 JPEN. March 1. 10:148607117699792.epub ahead of print.