There are millions of Americans taking one of several proton pump inhibitors or PPIs. These drugs are both prescription and over the counter. Taken primarily for heartburn, many versions have simply become part of our lifestyle. Television and magazine advertisements depict their use as a healthy lifestyle change. Most people are unaware of just how detrimental these acid blockers are. They are not the equivalent to taking a calcium-based antacid. While these too may have their issues, they are benign in comparison.