These are two very different formulas. The differences should be noted by clinicians and care providers, as they may significantly alter the overall metabolism of a patient.
First difference, primary sources of energy. Liquid Hope relies extensively on organic garbanzo beans, organic starchy vegetables, and organic flax seed oil. This provides the majority of the formula’s calories from low fructose vegetables and an oil exceptionally high in omega 3 fatty acids. We feel that based on scientific research (1,2,3,4) it is beneficial to have the lowest fructose content possible while still utilizing a vegetable-based recipe.
Our goal has always been to have our formulas provide low percentages of calories in the form of sugar, regardless of whether they are added or “naturally occurring”. We feel strongly that large amounts of naturally occurring sugar, particularly those rich in fructose such as with fruit purees, is an unnecessary metabolic risk for the production of excess uric acid (5).
Liquid Hope contains 9 grams of sugar, primarily from sweet potatoes, carrots, and peas. This represents 8% of calories and contains less than 2 grams of fructose. Nestle Organic Compleat contains 17 grams of sugar, much of which comes from mango or pear purees, both of which have high percentages of their overall sugar in the form of fructose. This represents 18% of calories in the way of sugar. The Nestle Organic Compleat nutrition profile does not have the fructose content of its formulas available at this time.
Second major difference, Liquid Hope has a 3:1 ratio of omega 3 fatty acids to omega 6 fatty acids. This is consistent with scientific research demonstrating reduced inflammation and improved outcomes in adults when compared to omega 6 fatty acid-dominant ratios (6,7,8). Nestle Organic Compleat does not have information available regarding their omega fatty acid ratio at this time.
Third major difference, Liquid Hope does not use chicken in any formula. We feel that it is better to avoid the significant amounts of omega 6 fatty acids found in chicken, particularly the dark meat used in some of Nestle Organic Compleat formulas. Although essential in very small amounts, larger amounts of the omega 6-fatty acid, arachidonic acid (AA), produces more inflammation. The dark meat of chicken is one of the richest sources of archidonic acid (9,10).
Fourth major difference, Liquid Hope contains 450 calories per pouch and Nestle Organic Compleat contains 380 calories.
~ John Bagnulo MPH, PhD.
1. Jensen T, Abdelmalek MF, Sullivan S, et al. Fructose and Sugar: A Major Mediator of Nonalcoholic Fatty Liver Disease. Journal of hepatology. 2018;68(5):1063-1075. doi:10.1016/j.jhep.2018.01.019.
2. Dornas WC, de Lima WG, Pedrosa ML, Silva ME. Health Implications of High-Fructose Intake and Current Research. Advances in Nutrition. 2015;6(6):729-737. doi:10.3945/an.114.008144.
3. Zhang D-M, Jiao R-Q, Kong L-D. High Dietary Fructose: Direct or Indirect Dangerous Factors Disturbing Tissue and Organ Functions. Nutrients. 2017;9(4):335.
4. Mosca A et al. Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents. J Hepatol. 2017 May;66(5):1031-1036.
5. White SJ et al. The effects of apples and apple juice on acute plasma uric acid concentration: a randomized controlled trial. Am J Clin Nutr. 2018 Feb 1;107(2):165-172.
6. Zhuang P et al. Polyunsaturated fatty acids intake, omega-6/omega-3 ratio and mortality: Findings from two independent nationwide cohorts. Clin Nutr. 2018 Mar 3. pii: S0261-5614(18)30082-7.
7. Kain V et al. Excess ω-6 fatty acids influx in aging drives metabolic dysregulation, electrocardiographic alterations, and low-grade chronic inflammation. Am J Physiol Heart Circ Physiol. 2018 Feb 1;314(2):H160-H169.
8. KITAGAWA M, HAJI S, AMAGAI T. Elevated Serum AA/EPA Ratio as a Predictor of Skeletal Muscle Depletion in Cachexic Patients with Advanced Gastro-intestinal Cancers. In Vivo. 2017;31(5):1003-1009. doi:10.21873/invivo.11161.
9. Beezhold BL, Johnston CS. Restriction of meat, fish, and poultry in omnivores improves mood: A pilot randomized controlled trial. Nutrition Journal. 2012;11:9.
10. Haug A, Olesen I, Christophersen OA. Individual variation and intraclass correlation in arachidonic acid and eicosapentaenoic acid in chicken muscle. Lipids in Health and Disease. 2010;9:37.